Bicarbonate (HCO₃⁻) in Dialysis Patient Plasma
This test measures the amount of bicarbonate, a key chemical in your blood that helps regulate acidity and balance. It’s often checked in people undergoing dialysis to ensure their blood chemistry stays stable.
["Bicarbonate levels help doctors monitor how well your body is handling acid-base balance during dialysis treatment."]
Key facts at a glance
- LOINC
- 54359-5
- Short code
- HCO3 p dialysis Plas-sCnc
- Synonyms
- HCO3 p dialysis Plas-sCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 22
- Ref high
- 28
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Dialysis Patients
Dialysis patients rely on machines to filter waste and excess fluids from their blood. Bicarbonate is crucial for maintaining proper blood pH, which prevents complications like muscle cramps, fatigue, or even heart problems. Low levels can indicate metabolic acidosis, while high levels may signal overcorrection. Your doctor may order this test to adjust dialysis settings or check for underlying health issues.
What to Expect Before the Test
You’ll likely have a small needle inserted into a vein (usually in your arm or hand) to draw a blood sample. The process takes just a few minutes, and you may feel a brief pinch. No special preparation is needed unless your doctor instructs otherwise. If you’re on dialysis, this test may be part of your regular treatment schedule.
What the Results Mean
Your results will show the concentration of bicarbonate in your plasma. While exact reference ranges vary by lab, abnormal levels can signal problems like poor dialysis function, kidney disease, or other metabolic disorders. Your healthcare team will discuss these findings with you during your follow-up visit.
Common Causes of Abnormal Results
Low bicarbonate levels may occur if your dialysis isn’t removing enough acid, or if you have conditions like diabetes, liver disease, or severe dehydration. High levels could indicate overcorrection of acidity or certain medications. Your doctor may also check for signs of kidney dysfunction or other metabolic imbalances.
Reference range
NCBI: HCO3- 22-28 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Monitoring Acid-Base Balance
Short name
Bicarbonate Level (Plasma)
Frequently asked questions
How often will I need this test?
What symptoms might indicate I need this test sooner?
Will this test affect my dialysis treatment?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy