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Arterial Hemoglobin Oxygen Saturation (SaO₂) via Calculated Arterial Blood Gas Analysis

Published: August 9, 2026Updated: August 17, 2026

This test measures how well your blood is carrying oxygen from your lungs to your body’s tissues. It’s often part of an arterial blood gas (ABG) panel to assess lung function and oxygen levels.

Quick summary

["Helps diagnose and monitor conditions affecting oxygen delivery in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
55781-9
Short code
Hct VFr Mar Calc
Synonyms
Hct VFr Mar Calc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
36
Ref high
50
Critical range
18 N/A – 60 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
calculated
CPT
85014
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

SaO₂ measures the percentage of oxygen bound to hemoglobin in your arterial blood. Normal oxygen saturation typically ranges between 95% and 100%, but this can vary based on health status and medical conditions. Low SaO₂ may indicate lung problems, heart issues, or other health concerns.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like shortness of breath, fatigue, or rapid heartbeat. It’s also used before surgeries, during critical illnesses, or to monitor chronic conditions like COPD or heart disease.

How Is the Test Performed?

A small sample of blood is taken from an artery (usually in your wrist) using a needle. The blood is analyzed immediately to measure oxygen saturation. This test is quick and usually done in a hospital or clinic setting.

What Are Common Results?

Results are reported as a percentage (e.g., 92%). A lower-than-normal SaO₂ may suggest poor lung function or breathing difficulties, while a higher-than-normal reading could indicate polycythemia (too many red blood cells).

Reference range

Adult males: 38-50%; Females: 36-44%N/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

SaO₂ (Arterial Oxygen Saturation)

Frequently asked questions

What causes low arterial oxygen saturation?
Low SaO₂ can result from conditions like chronic obstructive pulmonary disease (COPD), pneumonia, heart failure, or high altitudes. It may also occur due to breathing difficulties, anemia, or certain medications.
What if my SaO₂ is normal but I still feel short of breath?
Even if your SaO₂ is within normal limits, other factors like carbon dioxide levels (PaCO₂), pH, or blood gases may contribute to your symptoms. Your doctor might recommend additional tests or evaluate other aspects of your health.
Can I prepare for this test?
No special preparation is needed. You may be asked to sit or lie down comfortably, and the blood sample is taken quickly. Avoid smoking or heavy exercise just before the test if your doctor advises it.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy