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Hemoglobin Variants by Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures different types of hemoglobin in your blood using electrophoresis, a method that separates hemoglobin variants based on their electrical charge. It helps identify conditions like sickle cell disease or other inherited blood disorders.

Quick summary

["Helps diagnose blood disorders by detecting unusual hemoglobin forms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
107175-2
Short code
Hct VFr Prt
Synonyms
Hct VFr Prt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
36
Ref high
50
Critical range
18 N/A – 60 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85014
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like fatigue, pain in the bones or joints, frequent infections, or if they suspect genetic blood disorders. It’s also used to screen for conditions like thalassemia or sickle cell trait in certain populations.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw a blood sample. The test is quick and usually done in a lab setting.

How the Results Are Used

The results help determine if you have an inherited blood disorder. For example, abnormal bands on the electrophoresis result may indicate sickle cell disease or other hemoglobinopathies.

Common Conditions Linked to This Test

Conditions like sickle cell disease, thalassemia, or other hemoglobin variants may show up as distinct bands on the electrophoresis result. This test is critical for early diagnosis and management.

Reference range

Adult males: 38-50%; Females: 36-44%N/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin Electrophoresis

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains unusual hemoglobin forms that may indicate a genetic blood disorder, such as sickle cell disease or thalassemia. Your doctor will discuss the findings with you and may recommend further testing or treatment options.
How long does it take to get results?
Results are typically available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you once they have the results.
Can I eat or drink before this test?
No special diet or fasting is required for this test. You can eat and drink normally before your blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy