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Anti-HCV (Hepatitis C Virus) Antibody Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the Hepatitis C Virus (HCV) in your blood, which may indicate past or current infection with the virus.

Quick summary

["Helps identify if you’ve ever been exposed to Hepatitis C."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42506-6
Short code
HCV Ab CSF Ql
Synonyms
HCV Ab CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86803
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test looks for antibodies produced by your immune system in response to Hepatitis C virus proteins. These antibodies can appear after infection, even if you don’t yet have symptoms. This test is not used to diagnose active Hepatitis C infection but can confirm past exposure.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have risk factors for Hepatitis C, such as a history of blood transfusions before 1992, needle use, or exposure to infected blood. It’s also used in screening for those with unexplained liver issues or chronic liver disease.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you may feel slight discomfort.

What to Expect After the Test

After the blood draw, you may experience minor bruising or soreness at the site. Apply gentle pressure to reduce swelling. Avoid heavy lifting or strenuous activity for a short time.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results mean your body has produced antibodies against Hepatitis C, suggesting past infection. However, this does not confirm active infection. If you test positive, further testing (like HCV RNA) is needed to determine if the virus is still active. Negative results mean you likely have not been infected with Hepatitis C in the past year.

Short name

HCV Antibody

Frequently asked questions

What does a positive result mean?
A positive result indicates your immune system has recognized Hepatitis C virus proteins, which could mean you were previously infected. However, this test alone cannot tell if the virus is still active. You’ll need additional tests to check for current infection.
Can I get Hepatitis C from this test?
No, this test involves drawing blood from you and processing it in a lab. There is no risk of infection from the test itself.
How soon after exposure might I test positive?
Antibodies typically appear within 4 to 6 weeks after exposure to Hepatitis C, but it can take longer in some cases. If you suspect exposure, ask your doctor about timing for testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy