Anti-Hepatitis C Virus Antibody, Serum (Screening)

Why This Test Is Done

Your healthcare provider may order this test if you have risk factors for Hepatitis C, such as exposure to contaminated blood, long-term intravenous drug use, or a history of blood transfusions before 1992. It may also be recommended if you have unexplained liver issues or symptoms like fatigue, jaundice, or abdominal pain.

What to Expect Before the Test

No special preparation is needed. You’ll typically have a small needle inserted into your arm to draw blood from a vein. The process takes about 5 minutes, and you may feel a brief pinch. If you’re nervous, let your provider know so they can help make it more comfortable.

What the Results Mean

A positive result means your blood contains antibodies to Hepatitis C, suggesting past infection or exposure. A negative result means no detectable antibodies were found, but it doesn’t rule out infection—further testing (like PCR) is needed for confirmation. Always discuss results with your healthcare provider.

Next Steps and Follow-Up

If your screening test is positive, your provider will likely order additional tests, such as a confirmatory antibody test or viral load test, to determine if you have an active infection and its severity. Treatment options may be discussed based on the results.