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Hepatitis C Virus Antibody, Serum/Plasma (Screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the Hepatitis C virus, which your body makes if it has ever been exposed to the virus. Antibodies are proteins that help fight infections.

Quick summary

["A positive result may indicate past or current Hepatitis C infection; further testing is needed for confirmation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95237-4
Short code
HCV Ab SerPl-Imp
Synonyms
HCV Ab SerPl-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This screening test detects antibodies to Hepatitis C virus (HCV) in your blood. If your body has been exposed to the virus at any point, your immune system produces these antibodies. The test helps identify whether you may have been infected, even if you don’t currently have symptoms.

Why It’s Done

Doctors may order this test if you have risk factors for Hepatitis C, such as a history of blood transfusions before 1992, needle-sharing, or exposure to contaminated blood. It’s also used as part of routine screening in certain populations.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. The process usually takes a few minutes. If you’re nervous, let your healthcare provider know.

What to Expect After the Test

You may feel slight discomfort or bruising at the injection site. Apply gentle pressure to stop bleeding, and avoid rubbing the area. Most people return to normal activities immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HCV Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive screening result indicates your body may have been exposed to Hepatitis C virus, but it doesn’t confirm an active infection. You’ll need follow-up tests to determine if you have the virus and whether treatment is needed.
Can I get Hepatitis C from this test?
No, this test only checks for antibodies—it does not expose you to the virus. Blood tests use sterile equipment to prevent contamination.
What if my screening test is negative?
A negative result means your body did not detect antibodies to Hepatitis C at this time. However, if you have risk factors, you may need retesting later or additional screening. Always discuss your results with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy