C-reactive protein (CRP) by nephelometry (high-sensitivity)
This test measures a protein called C-reactive protein, which your body produces in response to inflammation. It helps assess low-level inflammation that may not be obvious from other tests.
["High-sensitivity CRP helps track subtle inflammation, often used alongside other tests for heart disease or autoimmune conditions."]
Key facts at a glance
- LOINC
- 51649-2
- Short code
- HCV c100p+5-1-1 Ab Ser Ql IB
- Synonyms
- HCV c100p+5-1-1 Ab Ser Ql IB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- CPT
- 86803
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why It’s Done
Your doctor may order this test to monitor chronic inflammation, evaluate risk for heart disease, or check for signs of conditions like rheumatoid arthritis or other autoimmune diseases. It’s sometimes used in research or follow-up for patients with known inflammatory conditions.
What to Expect
A small blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The test is quick and doesn’t require special preparation beyond standard blood draw guidelines.
How It Works
The lab uses a specialized technique called nephelometry to detect and measure tiny amounts of CRP in your blood. This method is highly sensitive, allowing it to pick up very low levels of inflammation that other tests might miss.
What the Results Mean
Results are reported in milligrams per liter (mg/L). Higher levels may indicate ongoing inflammation, while lower levels suggest reduced inflammation. Your doctor will interpret results in the context of your overall health and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
High-sensitivity CRP (hs-CRP)
Frequently asked questions
What does a high CRP level mean?
Why might my CRP level be elevated?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy