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C-Reactive Protein (CRP) by Immunoassay (High-Sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation, often used to check for low-grade inflammation or early signs of conditions like heart disease or infection.

Quick summary

["A simple blood test to monitor inflammation levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9610-7
Short code
HCV C33c Ab Ser Ql IB
Synonyms
HCV C33c Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

High-sensitivity CRP (hsCRP) is a blood test that detects very small amounts of C-reactive protein, a marker for inflammation. Unlike standard CRP, hsCRP can pick up subtle inflammation that might not be detected by other tests.

What to Expect During the Test

You’ll have a small needle inserted into your arm to draw a blood sample. The test is quick and usually done in a lab. Results help doctors assess your risk for conditions like heart disease or inflammation-related illnesses.

When Doctors Order This Test

Doctors may recommend hsCRP testing if you have risk factors for heart disease, chronic conditions like arthritis, or if you’re at higher risk for infections. It’s also used to monitor treatment progress for certain inflammatory diseases.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health. Elevated levels may signal inflammation, but they don’t always indicate a specific cause. Your doctor will discuss what the numbers mean for you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: hsCRP is a useful tool for identifying subtle inflammation that could contribute to long-term health risks. It helps guide preventive care and treatment decisions for conditions like cardiovascular disease or autoimmune disorders.

Short name

hsCRP

Frequently asked questions

What does a high hsCRP level mean?
A high hsCRP level may indicate inflammation in your body, which can be linked to conditions like heart disease, infections, or autoimmune disorders. Your doctor will review your results alongside other factors to determine next steps.
How often should I get this test?
Your doctor will decide how often to check your hsCRP based on your health needs. Some people may need it yearly, while others may need it more or less frequently depending on their condition and treatment plan.
Can lifestyle changes affect hsCRP levels?
Yes, lifestyle choices like diet, exercise, and managing stress can influence inflammation levels. Small changes, such as eating a heart-healthy diet or staying active, may help lower hsCRP over time. Always discuss these changes with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy