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Hepatitis C Virus (HCV) Antibody Screening and Confirmation Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the hepatitis C virus (HCV) in your blood. Antibodies are your body’s immune response to the virus, which can help identify past or current infection.

Quick summary

["Helps determine if you’ve been exposed to hepatitis C, even if you don’t yet have symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79189-7
Short code
HCV core Ag SerPl Ql IA
Synonyms
HCV core Ag SerPl Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Hepatitis C is a blood-borne virus that can cause long-term liver damage if untreated. This test is often used as a screening step to check for infection, especially if you’ve had risk factors like exposure to contaminated blood or needles.

How the Test Works

The test uses a blood sample (either serum or plasma) to detect specific antibodies produced by your immune system in response to the hepatitis C virus. The method combines screening and confirmation steps to ensure accuracy.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted to draw blood from your arm. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What the Results Mean

A positive result means your body has detected antibodies to hepatitis C, suggesting past or current infection. A negative result means no detectable antibodies were found, but this doesn’t rule out infection if testing was done too early. Follow-up testing may be needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in early detection of hepatitis C, allowing for prompt treatment to prevent liver damage. While antibodies indicate exposure, they don’t always mean active infection at the time of testing. Confirmatory testing may be required for diagnosis.

Short name

HCV Antibody Test

Frequently asked questions

What does a positive result mean for my health?
A positive result means your body has likely been exposed to the hepatitis C virus, but it doesn’t always mean you’re currently infected. You may need additional tests to confirm active infection and discuss next steps with your doctor.
How soon after exposure could I test positive?
Antibodies may take weeks to months to develop after exposure. If you suspect recent exposure, your doctor may recommend earlier testing or different types of tests to check for the virus itself.
Can I get hepatitis C from this test?
No, this test does not transmit hepatitis C. Blood samples are handled with strict safety protocols to prevent contamination.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy