Skip to content

Hepatitis C Virus Genotype Detection by Nucleic Acid Amplification Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the specific type (genotype) of the Hepatitis C virus in your blood, using a probe to detect its genetic material.

Quick summary

["Knowing your Hepatitis C genotype helps guide treatment choices and monitor your response to therapy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48575-5
Short code
HCV Gentyp Spec NAA+probe
Synonyms
HCV Gentyp Spec NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of Hepatitis C (such as fatigue, abdominal pain, or jaundice) or if you’ve been exposed to the virus. It’s also used to confirm infection after initial screening and to determine the best treatment plan.

How the Test Works

A small blood sample is taken and analyzed using a specialized probe that targets the genetic material of Hepatitis C. This method detects the virus’s presence and identifies which genotype you have, which can vary from 1 to 6.

What to Expect Before the Test

No special preparation is needed. You may have a slight pinch when the blood is drawn, but it usually takes only a few minutes. If you’re pregnant, have a bleeding disorder, or are on blood-thinning medication, let your provider know.

What the Results Mean

A positive result means you have Hepatitis C, and the genotype number indicates which strain you have. This information helps your doctor choose the most effective treatment, such as antiviral medications, tailored to your specific genotype.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Hepatitis C genotypes differ in how they respond to treatment and may require different durations or combinations of medications. Accurate genotyping ensures your treatment is as effective as possible and helps prevent long-term liver damage.

Short name

HCV Genotype Test (Nucleic Acid Probe)

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your provider will contact you once they’re ready.
What if my test is positive for Hepatitis C?
If your test is positive, your doctor will likely recommend further testing to confirm the diagnosis and guide treatment. They may also check your liver function and discuss antiviral therapy options tailored to your genotype.
Can I drink alcohol before this test?
It’s best to avoid alcohol for 24 hours before your blood draw, as it may affect test accuracy. However, your provider will give you specific instructions if needed.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy