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Anti-Hepatitis C Virus Immunoglobulin G (IgG) Antibody Test

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the hepatitis C virus (HCV) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["Helps determine if you’ve been exposed to hepatitis C virus in the past."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33462-3
Short code
HCV IgG Ser Ql IB
Synonyms
HCV IgG Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test looks for IgG antibodies specific to the hepatitis C virus. These antibodies develop after your body has been exposed to the virus, usually within weeks to months after infection. This test is often used as a screening tool to identify past or current hepatitis C infection.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have risk factors for hepatitis C, such as a history of blood transfusions before 1992, needle exposure, or living with someone who has hepatitis C. It can also be used to confirm a diagnosis if other tests are positive or to monitor treatment progress.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to detect the presence of HCV antibodies.

What Are the Results Typically Used For?

Positive results indicate past or current infection with hepatitis C. A negative result means you likely do not have active hepatitis C infection at this time, but you may still need further testing or follow-up based on your risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HCV IgG Antibody

Frequently asked questions

What Does a Positive Test Mean?
A positive result suggests you may have been infected with hepatitis C at some point. You may need additional tests, such as HCV RNA testing, to determine if the infection is active and to guide treatment decisions.
What If My Test Result Is Negative?
A negative result means you likely do not currently have an active hepatitis C infection. However, if you have risk factors for hepatitis C, your healthcare provider may recommend follow-up testing or monitoring to ensure you are not at risk.
How Often Should I Get This Test?
The frequency of testing depends on your risk factors and medical history. Your healthcare provider will determine the best schedule based on your individual needs, such as after exposure, during treatment, or as part of routine health checks.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy