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Human Chorionic Gonadotropin (HCG) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of human chorionic gonadotropin (HCG), a hormone produced after pregnancy begins. It helps detect early pregnancy or certain conditions like ectopic pregnancy.

Quick summary

["HCG levels can signal pregnancy or medical concerns needing further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104714-1
Short code
HCV RNA SerPl-Log IU
Synonyms
HCV RNA SerPl-Log IU
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HCG Used For?

HCG is primarily used to confirm pregnancy, especially in early stages when other tests may not be reliable. It can also help monitor high-risk pregnancies or diagnose conditions like molar pregnancy or gestational trophoblastic disease. Doctors may also use it to check for ectopic pregnancies or to evaluate fertility treatments.

When Might You Need This Test?

You might need an HCG test if you have missed periods, suspect pregnancy, or experience symptoms like nausea, breast tenderness, or unusual vaginal bleeding. It’s also used during fertility treatments, after miscarriage, or in cases where pregnancy complications are suspected.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where HCG levels are measured using a sensitive immunoassay method. The test is quick and usually done in a doctor’s office or clinic.

What Are Common Results?

Results are reported in international units per milliliter (IU/mL). Very low or undetectable levels may mean no pregnancy. Rising levels over time can confirm pregnancy progression. Very high levels may indicate complications like molar pregnancy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HCG is critical for early pregnancy diagnosis and monitoring. It’s the hormone detected in pregnancy tests and used to track fetal development. Abnormal levels can signal risks like miscarriage, ectopic pregnancy, or trophoblastic diseases, prompting further medical evaluation.

Short name

HCG Test

Frequently asked questions

Why do some people get multiple HCG tests during pregnancy?
Multiple HCG tests are often done to monitor how quickly the hormone rises, which helps assess fetal health and detect complications early. For example, if levels rise too slowly or too quickly, it may signal issues like a failed implantation or molar pregnancy.
What happens if my HCG levels are too low?
Low HCG levels can indicate a possible miscarriage, ectopic pregnancy, or early pregnancy loss. Your doctor may recommend additional tests or monitoring to determine the cause and next steps.
Can HCG levels be affected by other conditions?
Yes, conditions like kidney disease, liver disease, or certain medications (e.g., some chemotherapy drugs) can affect HCG levels. If you suspect these conditions, discuss them with your healthcare provider before or after testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy