Hepatitis C Virus RNA (Quantitative) – Plasma
This test measures the amount of Hepatitis C virus genetic material in your plasma to check for active infection.
["Helps diagnose and monitor Hepatitis C virus infection."]
Key facts at a glance
- LOINC
- 49372-6
- Short code
- HCV RNA Spec NAA+probe-Log#
- Synonyms
- HCV RNA Spec NAA+probe-Log#
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- CPT
- 86803
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms of Hepatitis C, such as fatigue, abdominal pain, or unexplained liver issues, or if you’ve been exposed to the virus. It’s also used to confirm infection after initial screening or to track how your treatment is progressing.
What to Expect Before the Test
No special preparation is needed. You’ll typically have a small needle inserted into your arm to draw a blood sample. If you’re on blood thinners, let your provider know beforehand.
What the Test Results Mean
A positive result means you have detectable Hepatitis C virus RNA, confirming active infection. A negative result means no detectable virus was found in the sample at the time of testing. Results are usually reported in viral load units (e.g., IU/mL), but your provider will interpret them in context with your medical history.
How Results Are Used
Your provider will use these results to guide treatment decisions, such as antiviral medications, and to monitor your liver health over time. If you’re treating an infection, follow-up tests may be scheduled to check response to therapy.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Hepatitis C virus RNA testing is critical for diagnosing active infection, guiding treatment decisions, and ensuring proper management of liver disease. Early detection and treatment can prevent long-term liver damage, including cirrhosis or liver cancer. This test helps track viral load changes during treatment to assess effectiveness and adjust therapy as needed.
Short name
HCV RNA (Plasma)
Frequently asked questions
What does a positive HCV RNA result mean?
How often should I get this test if I have Hepatitis C?
Can I drink alcohol before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy