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Hepatitis C Virus RNA (Quantitative) – Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Hepatitis C virus genetic material in your blood to check for active infection.

Quick summary

["Helps determine if you have active Hepatitis C and guides treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49605-9
Short code
HCV RNA Spec NAA+probe-Log IU
Synonyms
HCV RNA Spec NAA+probe-Log IU
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have risk factors for Hepatitis C, such as exposure to contaminated blood, long-term organ transplant, or injection drug use. It may also be used to monitor treatment progress or check for recurrence after treatment.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

What the Test Results Mean

A positive result means you have detectable Hepatitis C virus RNA, indicating active infection. A negative result means no active virus was found in the sample at the time of testing. Results are often reported as a viral load (amount of virus), which helps guide treatment planning.

How This Test Helps Your Care

This test helps your healthcare provider assess whether you have an active Hepatitis C infection, monitor treatment effectiveness, and adjust therapy as needed to manage the virus and prevent long-term liver damage.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Hepatitis C Virus RNA Testing

Short name

HCV RNA (Plasma)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–2 weeks, depending on lab processing times. Your provider will contact you once results are ready.
Can I drink alcohol before this test?
Alcohol use before testing does not affect the test itself, but it may impact liver health. Avoid heavy alcohol use before and during treatment if recommended by your provider.
What if my test results are positive for Hepatitis C?
A positive result means you need treatment to clear the virus. Your healthcare provider will work with you to choose the right antiviral medications and monitor your response over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy