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Hepatic Cytochrome P450 Reductase Activity (Serum/Plasma Probe)

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of an enzyme involved in liver metabolism, which helps assess how well your liver can process certain drugs and chemicals.

Quick summary

["This test supports liver function and drug metabolism monitoring."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5011-2
Short code
HCV RNA Tiss Ql NAA+probe
Synonyms
HCV RNA Tiss Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86803
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have liver concerns, are taking medications metabolized by cytochrome P450 enzymes, or if you need to evaluate how your liver handles certain substances.

What to Expect Before the Test

No special preparation is typically required, but you may need to fast or avoid certain medications for a few days beforehand. Bring any medications you’re currently taking to your appointment.

How the Test Works

A small blood sample is drawn from a vein in your arm. The sample is analyzed to measure enzyme activity levels, often using a specialized probe method to detect metabolic function.

What the Results Mean

Results help identify how efficiently your liver processes substances. Abnormal findings may indicate liver dysfunction or impaired drug metabolism, guiding further medical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cytochrome P450 Reductase Activity

Frequently asked questions

What does a low result mean?
A low result may suggest reduced liver function or impaired ability to metabolize certain substances, potentially affecting how your body processes medications or toxins.
Can diet affect this test?
Dietary changes alone won’t directly alter enzyme activity measured here, but certain foods or supplements may interact with medications metabolized by these enzymes. Always follow your provider’s guidance.
How often should this test be repeated?
Frequency depends on your health status and treatment plan. Your provider will determine if follow-up testing is needed, typically based on symptoms, lab trends, or medication adjustments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy