HDL Cholesterol, Serum/Plasma
Measures high-density lipoprotein (HDL) cholesterol in blood. HDL helps transport cholesterol away from arteries to the liver.
["HDL cholesterol is a measure of the “good” cholesterol that may help protect against heart disease."]
Key facts at a glance
- LOINC
- 70200-1
- Short code
- HDLc SerPl-sRto
- Synonyms
- HDLc SerPl-sRto
- Category
- lipid
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 40
- Ref high
- 60
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83700
- SNOMED
- 113079008
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This blood test measures the amount of cholesterol carried by high-density lipoprotein (HDL). HDL is often called “good” cholesterol because it helps move cholesterol back toward the liver for removal.
Why might I need this test?
This test is commonly used to assess cardiovascular risk, especially when total cholesterol, LDL cholesterol, triglycerides, or other risk factors are being evaluated. It may also be part of routine lipid screening.
How is the test performed?
A blood sample is drawn from a vein and analyzed in a laboratory to determine the concentration of HDL cholesterol. The exact laboratory method does not change the basic meaning of the result.
How do I prepare for the test?
You may be asked to fast for several hours before the blood draw, depending on the laboratory and the other tests being ordered. Drinking water is generally acceptable, and you should follow the specific instructions provided by your healthcare professional.
Reference range
Adult males: >40 mg/dL; Females: >50 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A low HDL cholesterol level can be associated with increased cardiovascular risk, particularly when other risk factors are present. A high level is generally viewed as favorable, but HDL results should be interpreted with the rest of the lipid profile and your overall health history.
Short name
HDL Cholesterol
Frequently asked questions
Is HDL cholesterol the same as total cholesterol?
Do I need to fast before this test?
Can lifestyle changes improve HDL cholesterol?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy