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High-Density Lipoprotein Cholesterol, Fluid — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of high-density lipoprotein cholesterol in a fluid sample. HDL helps transport cholesterol away from arteries.

Quick summary

["HDL cholesterol is one of the main blood lipid measurements used to assess cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17082-9
Short code
HDL Fld-mCnc
Synonyms
HDL Fld-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
40
Ref high
60
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83700
SNOMED
113079008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures high-density lipoprotein (HDL) cholesterol in a fluid sample. HDL is a protein that carries cholesterol through the blood and may help move excess cholesterol from tissues back toward the liver.

Why might I need this test?

HDL cholesterol is usually measured as part of a cholesterol profile to help assess cardiovascular risk. A health care professional may also order it when monitoring lipid levels, weight-management treatment, or medications that affect cholesterol.

How is the test performed?

A laboratory analyzes the submitted fluid using an appropriate method to determine the amount of HDL cholesterol present. The sample type and collection requirements depend on the specific laboratory order.

How do I prepare for the test?

No special preparation is commonly required for the HDL measurement itself. Follow the instructions provided for collecting the fluid sample, and ask your health care professional whether fasting is needed for the accompanying cholesterol tests.

Reference range

Adult males: >40 mg/dL; Females: >50 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HDL Cholesterol

Frequently asked questions

Does a high HDL cholesterol level mean I am completely protected from heart disease?
No. Higher HDL is generally considered favorable, but it does not eliminate the risk of cardiovascular disease. Other cholesterol measurements, blood pressure, diabetes status, smoking, and family history also matter.
Why is my HDL result considered alongside other cholesterol tests?
Cardiovascular risk is assessed using the full cholesterol profile rather than one value alone. HDL, LDL cholesterol, total cholesterol, and triglycerides provide complementary information.
Can medications or lifestyle changes affect HDL cholesterol?
Yes. Exercise, weight changes, smoking status, diet, and certain medicines can influence HDL cholesterol. Your health care professional can help interpret changes in the context of your overall health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy