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Hemoglobin A1c (HbA1c) with 24-hour urine collection for albumin excretion rate (AER)

Published: August 9, 2026Updated: August 16, 2026

This test measures your long-term blood sugar control and checks for kidney damage by tracking small amounts of protein (albumin) in your urine over 24 hours.

Quick summary

["Helps monitor diabetes management and kidney health in people with diabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22330-5
Short code
HDV Ab Ser-aCnc
Synonyms
HDV Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The **HbA1c** test reflects your average blood sugar levels over the past 2–3 months by measuring the percentage of hemoglobin (a protein in red blood cells) that has sugar attached. This provides a snapshot of how well your diabetes is controlled over time. The **24-hour urine albumin test** detects tiny amounts of albumin (a protein) in your urine, which can indicate early kidney damage, especially in people with diabetes.

Why Is This Test Important?

Combining these tests helps doctors assess both your blood sugar control and kidney function. High HbA1c levels suggest poor diabetes management, while elevated urine albumin may signal kidney strain, even if your blood sugar seems well-controlled otherwise.

How Is This Test Done?

You’ll provide a blood sample (for HbA1c) and a 24-hour urine collection (for albumin). The urine sample is collected in a container over the full day, while the blood test is typically drawn from a vein in your arm. Results are analyzed in a lab to determine your levels.

What Might These Results Tell Your Doctor?

High HbA1c (typically ≥6.5%) suggests poor diabetes management and may require lifestyle or medication adjustments. Elevated urine albumin (above normal thresholds) may prompt further kidney tests or closer monitoring of blood pressure and diabetes control.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: This test is critical for diabetes management because it bridges blood sugar control and kidney health. High urine albumin is a key marker for diabetic nephropathy (kidney disease), which can progress silently. Early detection allows for timely interventions to prevent complications like kidney failure or heart disease.

Short name

HbA1c + Urine Albumin Test

Frequently asked questions

What does an abnormal HbA1c result mean?
An abnormal HbA1c result (typically above 7% or below 6.5% depending on your health) may indicate your blood sugar levels haven’t been well-managed. Your doctor will discuss next steps, such as adjusting medications, diet, or exercise plans.
What does an abnormal urine albumin result mean?
An abnormal urine albumin result (above normal levels) suggests your kidneys may be struggling, especially if you have diabetes. This doesn’t always mean kidney disease is advanced, but it’s a sign your doctor will monitor closely to prevent further damage.
How often should I get this test?
Your doctor will determine how often you need this test based on your diabetes management plan. Typically, HbA1c tests are done every 3–6 months, while urine albumin tests may be checked annually or more frequently if you have kidney risk factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy