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Serum or plasma mass concentration of vitamin D binding protein (DBP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein, a protein in your blood that helps transport vitamin D. It can be part of a broader evaluation for vitamin D status or related metabolic conditions.

Quick summary

["This test helps assess how vitamin D is transported in your blood and may support vitamin D-related health evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43280-7
Short code
HDV Ag Ur-mCnc
Synonyms
HDV Ag Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if they suspect vitamin D deficiency, metabolic bone disorders, or conditions affecting protein transport in the blood. It could also be part of a screening for genetic or hormonal imbalances.

What Does This Test Measure?

Vitamin D binding protein (DBP) is a carrier protein that binds to vitamin D in the bloodstream. Elevated levels may indicate certain genetic conditions or kidney function changes, while lower levels could be associated with vitamin D metabolism issues.

Sample Collection and Preparation

This test typically uses a blood sample drawn from a vein. The blood is processed to separate serum or plasma, which is then analyzed for DBP concentration using specialized laboratory techniques.

What Does a High or Low Level Mean?

Interpretation of results depends on clinical context. High levels might suggest inherited conditions like familial chylomicronemia syndrome or kidney-related protein abnormalities. Low levels alone may not indicate vitamin D deficiency but could be part of a broader metabolic assessment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D Binding Protein Level

Frequently asked questions

What does a high vitamin D binding protein level mean?
A high level may indicate genetic conditions like familial chylomicronemia syndrome or kidney-related protein abnormalities. Your provider will consider your symptoms, medical history, and other test results for a full assessment.
What does a low vitamin D binding protein level mean?
A low level alone may not directly indicate vitamin D deficiency but could be part of a broader evaluation for metabolic or genetic conditions. Your provider will review your clinical picture and other test results to guide interpretation.
How is this test different from a vitamin D blood test?
This test specifically measures vitamin D binding protein levels, not vitamin D itself. Vitamin D tests (like 25-hydroxy vitamin D) assess the actual vitamin D in your bloodstream, while this test evaluates how vitamin D is transported and managed by your body’s proteins.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy