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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and evaluates how well your kidneys filter blood, using a 24-hour urine sample.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54049-2
Short code
HEDIS 2009-13 LSC-A
Synonyms
HEDIS 2009-13 LSC-A
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8.5
Ref high
10.5
Critical range
6 N/A – 14 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82310
SNOMED
110744001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Blood Sugar Control

HbA1c reflects your long-term blood sugar levels, giving doctors a clearer picture than daily glucose checks. It’s used to diagnose diabetes and monitor treatment effectiveness over time.

How the Kidney Filter Test Works

The 24-hour urine sample helps calculate creatinine clearance, a measure of kidney function. This helps assess how well your kidneys remove waste products from your blood.

What to Expect Before Your Test

You’ll collect all urine for 24 hours in a special container. Drink plenty of water to help your kidneys produce urine, but avoid special diets unless instructed by your doctor.

What the Results Mean

High HbA1c levels may indicate poor blood sugar control, while abnormal creatinine clearance could signal kidney issues. Your doctor will interpret results in the context of your overall health.

Reference range

Adult: 8.5-10.5 mg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + CrCl 24h

Frequently asked questions

Why do I need both HbA1c and kidney function tests together?
Combining these tests helps identify whether high blood sugar is affecting kidney function or vice versa. For example, diabetes can damage kidneys, and kidney disease may require adjustments to diabetes medications.
Can I eat or drink anything special before the urine collection?
No special diet is needed, but drink enough water to produce urine throughout the day. Avoid alcohol or medications that may affect urine color unless your doctor advises otherwise.
How often should I have this test?
Your doctor will determine frequency based on your health needs—typically every 3–6 months for people with diabetes, but more often if you have kidney concerns or other complications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy