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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and estimates your kidney function using a urine sample.

Quick summary

["Helps track diabetes management and kidney health in one combined result."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57807-0
Short code
HEDIS 2010 PPC-C
Synonyms
HEDIS 2010 PPC-C
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Diabetes Management

HbA1c reflects your blood sugar control over time, while creatinine clearance assesses kidney function. Together, they provide a clearer picture of how well your body is managing both conditions.

How the Test Works

Your blood is drawn to measure HbA1c levels, and a 24-hour urine sample is collected to estimate kidney function using creatinine clearance. This helps healthcare providers assess long-term blood sugar control and kidney health simultaneously.

What to Expect Before the Test

No special preparation is needed for HbA1c, but you’ll need to collect a full 24-hour urine sample (starting and ending with your first morning urine). Follow your provider’s instructions carefully to ensure accurate results.

Common Causes of Abnormal Results

High HbA1c levels may indicate poor blood sugar control, while abnormal creatinine clearance could signal kidney issues. Both may require adjustments to diet, medication, or lifestyle.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This combined test helps identify both diabetes-related blood sugar problems and kidney function decline, allowing for more targeted treatment planning.

Short name

HbA1c + eGFR

Frequently asked questions

Why do I need a 24-hour urine sample for this test?
The urine sample helps estimate how well your kidneys filter waste (creatinine clearance). A full 24-hour collection ensures an accurate measure of kidney function alongside your blood sugar levels.
Can I take medications or eat normally before this test?
For HbA1c, no restrictions apply. For creatinine clearance, avoid diuretics or excessive fluids unless instructed by your provider to prevent false results.
What if my HbA1c or kidney test results are out of range?
If results are abnormal, your healthcare team will discuss next steps, which may include adjusting medications, monitoring diet, or further testing to prevent complications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy