Hepatic Enzymatic Drug Toxicity Profile (Serum/Plasma)
This test measures levels of certain enzymes and substances in your blood that can indicate how your liver processes medications or toxins. It helps assess potential liver strain from drug exposure.
["This screening helps identify if your liver is handling drugs safely or if toxicity may be occurring."]
Key facts at a glance
- LOINC
- 60483-5
- Short code
- HEDIS 2010 PPC-C Toxo
- Synonyms
- HEDIS 2010 PPC-C Toxo
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates specific biomarkers that reflect liver function and drug metabolism. These may include enzymes like those involved in detoxification pathways and metabolites of common medications.
Why It’s Ordered
Your healthcare provider may order this test if you’re taking multiple medications, have liver concerns, or are at risk for drug-related liver damage. It helps monitor how your body processes substances safely.
Common Uses in Patient Care
This screening is often used in cases of suspected drug-induced liver injury, especially in patients on long-term medications or those with pre-existing liver conditions.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma for testing. This test does not require fasting unless specified by your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Drug Toxicity Screen
Frequently asked questions
Your liver plays a critical role in detoxifying drugs and toxins. Elevated levels of certain enzymes or metabolites in this test may signal that your liver is working harder than usual, potentially due to drug exposure or other stressors.
How often should I get this test? The frequency depends on your medical history, medications, and healthcare provider’s recommendations. Follow-up testing may be needed if you experience symptoms like fatigue, jaundice, or abdominal pain.
What if I’m pregnant or breastfeeding? If you’re pregnant, breastfeeding, or have specific health conditions, inform your healthcare provider before testing. They may adjust testing needs based on your situation.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy