Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and helps assess kidney function by combining hemoglobin A1c with a 24-hour urine creatinine clearance calculation.

Quick summary

["Helps track long-term blood sugar control and kidney health in tandem."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC: 67768-2
Short code: HEDIS 2012-13 PPC-C ABO+Rh
Synonyms: HEDIS 2012-13 PPC-C ABO+Rh
Category: chemistry
Sample: serum
Container: Red-top tube (SST)
Units: N/A
Fasting: false
Population: adult
Sex: all
Age range: 18–65 years
Specimen volume: 5 mL
Stability: Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max: 500
Lipemia max: 1000
Icterus max: 500
TAT: 4–24 hours
Order: routine

Why This Test Matters for Blood Sugar Management

HbA1c reflects your blood glucose levels over time, giving doctors a clearer picture of how well your diabetes or prediabetes is managed. This test is especially useful for long-term planning because it accounts for daily fluctuations in blood sugar.

Understanding Kidney Function in Diabetes

The creatinine clearance part of this test evaluates how well your kidneys filter waste products. Diabetes can damage kidneys over time, so this measurement helps identify early signs of kidney strain alongside your blood sugar control.

How the Test Works: Two Parts Combined

Your blood is drawn for HbA1c, which measures the percentage of hemoglobin coated with sugar. A 24-hour urine sample is collected to assess creatinine levels and calculate how efficiently your kidneys filter waste. This combined approach provides a more comprehensive view of your metabolic health.

What Normal Results Mean

While specific ranges vary by lab, a lower HbA1c percentage typically indicates better blood sugar control. A creatinine clearance result within expected limits suggests healthy kidney function, though individual results depend on age, sex, and overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + CrCl (24h urine)

Frequently asked questions

Why might my doctor order this test?

Your doctor may recommend this test if you have diabetes, prediabetes, or if they suspect kidney issues. It helps monitor both blood sugar control and kidney function together, which is critical for preventing complications like nerve damage or kidney disease.

What do abnormal results mean?

High HbA1c levels may indicate poor blood sugar management, while low creatinine clearance could signal kidney problems. Either result may prompt further testing or adjustments to your treatment plan.

How often should I get this test?

Typically, HbA1c is checked every 3–6 months for people with diabetes. The 24-hour urine creatinine clearance may be done less frequently unless your doctor notes concerns about kidney function.

Sources

1
MedlinePlus — Laboratory TestsSource
2
Lab Tests OnlineSource
3
Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy