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Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Creatinine Clearance

Published: August 9, 2026Updated: August 16, 2026

This test measures your long-term blood sugar levels (HbA1c) and evaluates how well your kidneys filter waste through a 24-hour urine sample.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
67760-9
Short code
HEDIS 2012 CWP-D
Synonyms
HEDIS 2012 CWP-D
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why HbA1c Matters for Diabetes Control

HbA1c reflects your average blood sugar levels over the past 2–3 months, giving doctors a clearer picture of how well your diabetes is managed. High levels may indicate poor control, while stable or low levels suggest effective treatment.

How Urine Creatinine Works in This Test

The urine creatinine test assesses how well your kidneys filter waste by measuring creatinine levels in a 24-hour urine sample. This helps determine your kidney function alongside your HbA1c.

What to Expect Before Your Test

For the urine portion, collect all urine for 24 hours (typically from one morning to the next morning). Drink plenty of water to help urine flow. For the blood (HbA1c), no special preparation is needed, but fasting is not required.

What the Results Mean

HbA1c results alone are interpreted as usual (e.g., <5.7% is normal, 5.7–6.4% is prediabetes, ≥6.5% is diabetes). Urine creatinine results are compared to your body weight to calculate creatinine clearance, which helps assess kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Combining HbA1c and Kidney Function

Short name

HbA1c + Urine Creatinine

Frequently asked questions

Why is this test important for my health?
This test helps doctors monitor both your blood sugar control and kidney health simultaneously. High HbA1c with abnormal creatinine clearance may indicate diabetes-related kidney damage, which can worsen over time if untreated.
What do abnormal results mean?
An elevated HbA1c suggests poor blood sugar control, while a low creatinine clearance may indicate kidney issues. Together, these results can guide treatment adjustments, such as medication changes or lifestyle recommendations.
How often should I get this test?
Typically, HbA1c is checked every 3–6 months for people with diabetes. Urine creatinine clearance may be included less frequently unless your doctor suspects kidney problems.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy