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Hemoglobin A1c (HbA1c) with Pregnancy Adjustment

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past 2–3 months, adjusted for pregnancy-related changes in hemoglobin composition. It helps assess long-term glucose control in pregnant individuals.

Quick summary

["This adjusted HbA1c helps track blood sugar trends safely during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74253-6
Short code
HEDIS 2014 Preg
Synonyms
HEDIS 2014 Preg
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HbA1c and Why Is It Special in Pregnancy?

HbA1c reflects your body’s average blood sugar levels over time by measuring the percentage of hemoglobin molecules bonded to glucose. In pregnancy, hemoglobin composition changes, so a standard HbA1c may not fully reflect true glucose control. This adjusted version accounts for those changes to provide a clearer picture of your blood sugar management.

How Is This Test Different from a Regular HbA1c?

Unlike standard HbA1c, which uses general reference ranges, this pregnancy-adjusted test applies modified thresholds to better reflect how pregnancy affects hemoglobin and glucose metabolism. It may also be interpreted differently to align with obstetric guidelines for gestational diabetes screening.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if you have gestational diabetes, pregestational diabetes, or if your blood sugar levels are consistently high during pregnancy. It helps monitor how well your body is managing glucose to prevent complications for both you and your baby.

How Is This Test Performed?

A small blood sample is taken from your arm, similar to other blood tests. The sample is processed to measure the adjusted HbA1c level, which is then reported as a percentage or ratio reflecting your average blood sugar over the past few months.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High or low HbA1c levels during pregnancy can indicate poor glucose control, increasing risks for complications like preterm birth, low birth weight, or long-term health issues for both mother and child. This adjusted test helps identify trends early, allowing for timely interventions to support healthy outcomes.

Short name

HbA1c (Pregnancy-Adjusted)

Frequently asked questions

What Does an Abnormal Result Mean?
An abnormal result may signal gestational diabetes or preexisting diabetes that requires closer monitoring. Your doctor will discuss next steps, such as lifestyle changes, medication adjustments, or further testing to manage your blood sugar safely.
How Often Should I Get This Test?
Your doctor will determine the frequency based on your pregnancy history, blood sugar trends, and overall health. Typically, it may be checked at key milestones (e.g., first trimester, second trimester, or near delivery). Follow their guidance to stay informed.
Can I Prepare for This Test?
No special preparation is needed, but avoid eating or drinking (except water) for 8–12 hours before the test if instructed. Wear comfortable clothing for the blood draw, and let your doctor know if you’re taking diabetes medications or have any allergies.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy