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Colorectal Cancer Screening: Fecal Immunochemical Test (FIT) for Occult Blood (2020 Guideline Compliance)

Published: August 9, 2026Updated: August 16, 2026

This test detects hidden (occult) blood in your stool, which may signal early signs of colorectal cancer or other gastrointestinal issues.

Quick summary

["Early detection can improve treatment options and outcomes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96063-3
Short code
HEDIS MY 2020 CT Colongrphy
Synonyms
HEDIS MY 2020 CT Colongrphy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Colorectal cancer screening is crucial for early detection, often before symptoms appear. This test helps identify small amounts of blood in your stool that may come from polyps, early-stage cancer, or other gastrointestinal conditions. It’s a simple, painless way to monitor your risk and catch issues early.

How the Test Works

A small sample of your stool is collected (often at home) and tested for hidden blood using a chemical reaction that detects hemoglobin. This test is non-invasive and doesn’t require special preparation beyond normal bowel movements.

What to Expect Before the Test

No special preparation is needed. You may collect a sample during your normal bowel movements, or your healthcare provider may collect it during a routine office visit. If done at home, follow the instructions provided to ensure accuracy.

What to Expect During the Test

The test involves placing a small stool sample on a special card or device. Results are typically available within minutes. If you’re tested in a lab, a sample is sent for analysis, but results are usually ready within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

FIT Occult Blood Test

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of occult blood, which may require further testing (such as a colonoscopy) to investigate potential causes like polyps, inflammation, or early cancer. Follow-up depends on your healthcare provider’s recommendations.
What does a negative result mean?
A negative result means no detectable blood was found in this sample, but it doesn’t guarantee you don’t have colorectal cancer or another issue. Regular screening is still important, especially if you have risk factors.
How often should I get this test?
According to the 2020 guidelines, adults aged 50–75 should get this test every one to two years, depending on your health history and risk factors. Your healthcare provider will determine the best schedule for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy