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Low-Density Lipoprotein (LDL) Cholesterol Test — HEDIS Measurement Year 2020

Published: August 9, 2026Updated: August 16, 2026

Measures LDL (“bad”) cholesterol in the blood. It may be reported directly or calculated from other cholesterol results to help assess cardiovascular risk.

Quick summary

["LDL cholesterol results help estimate how much cholesterol-rich particle buildup may be occurring in the arteries."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96071-6
Short code
HEDIS MY 2020 LDL-C Tests
Synonyms
HEDIS MY 2020 LDL-C Tests
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures low-density lipoprotein (LDL) cholesterol, sometimes called “bad” cholesterol. LDL carries cholesterol in the blood and is associated with fatty plaque buildup in arteries.

Why might I need this test?

An LDL cholesterol test may be used to assess cardiovascular risk, guide cholesterol-lowering treatment, or monitor the response to diet, exercise, or medication. The HEDIS reference in the test identifier refers to a 2020 healthcare quality-measure context.

How is the test performed?

A blood sample is drawn and analyzed in a laboratory. LDL cholesterol may be measured directly or calculated using results for total cholesterol, HDL cholesterol, and triglycerides.

How do I prepare for the test?

Fasting is often not required, but you may be asked to fast if the laboratory is also checking triglycerides or if your clinician requests it. Follow the instructions provided with the test order.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A high LDL cholesterol result may increase the risk of atherosclerosis and cardiovascular disease. A low result may reflect cholesterol-lowering treatment or other circumstances that should be interpreted by a clinician. LDL levels are best considered along with total cholesterol, HDL cholesterol, triglycerides, and personal cardiovascular risk factors.

Short name

LDL cholesterol test

Frequently asked questions

Is a higher LDL cholesterol result worse?
Generally, yes. Higher LDL cholesterol is associated with a greater risk of plaque buildup and cardiovascular disease, although overall risk also depends on other health factors.
Do I need to fast before this test?
Fasting is often unnecessary for an LDL-only test. It may be required when triglycerides are also being measured, so follow any preparation instructions from the laboratory or clinician.
Does the test distinguish among different types of LDL particles?
A standard LDL cholesterol test usually provides a total LDL cholesterol result rather than a detailed analysis of individual LDL particle types. Additional testing may be needed for that information.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy