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Prostate-Specific Antigen (PSA) Level Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prostate-specific antigen (PSA), a protein produced by both healthy and cancerous prostate cells. It helps assess prostate health, detect early signs of prostate cancer, or monitor treatment progress.

Quick summary

["PSA tests are used to evaluate prostate health and potential cancer risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15301-5
Short code
Height Prostate US.meas
Synonyms
Height Prostate US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a PSA test to check for prostate issues, such as an enlarged prostate (benign prostatic hyperplasia), prostate infection, or prostate cancer. It may also be used during routine check-ups, especially for men at higher risk, or to monitor existing prostate conditions.

What to Expect Before the Test

You can eat and drink normally before the test. Avoid ejaculation for 2–3 days before testing, as it can temporarily raise PSA levels. Tell your doctor about any medications you’re taking, as some may affect results.

What Happens During the Test?

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. The sample is sent to a lab for analysis.

What Do the Results Mean?

PSA levels vary widely among individuals. A single test result alone doesn’t diagnose prostate cancer—it’s used alongside other tests and clinical findings. Results may be discussed with your doctor to guide further evaluation if needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

PSA Blood Test

Frequently asked questions

What Are Common PSA Levels?
PSA levels can’t be interpreted in isolation. They depend on age, overall health, and other factors. A low PSA doesn’t always mean no prostate issues, while an elevated PSA may prompt further testing to rule out cancer or other conditions.
How Often Should I Get This Test?
The frequency depends on your age, symptoms, and risk factors. Your doctor will recommend a schedule based on your individual needs, such as regular screenings for men over 50 or those with a family history of prostate cancer.
Does This Test Have Side Effects?
Most people experience only minor discomfort or bruising at the injection site. Rarely, there may be a slight reaction like redness or swelling, but these are usually temporary.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy