Heparan sulfate proteoglycan (e.g., syndecan-1) in plasma or serum
This test measures a specific type of protein-carbohydrate complex found in blood, which plays a role in regulating blood clotting and cell signaling.
["Understanding your heparan sulfate levels may help assess certain blood or tissue functions."]
Key facts at a glance
- LOINC
- 104113-6
- Short code
- Heparan-N-Sulfatase DBS-cCnc
- Synonyms
- Heparan-N-Sulfatase DBS-cCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 2
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Measuring?
Heparan sulfate is a complex molecule made up of proteins and sugar chains (glycosaminoglycans) that are part of the cell surface or extracellular matrix. In this test, we measure the concentration of heparan sulfate in your blood plasma or serum. This molecule helps control blood clotting and can also influence how other substances interact with cells in your body.
Why Might You Need This Test?
Your healthcare provider may order this test if they suspect conditions affecting heparan sulfate levels, such as certain genetic disorders, bleeding disorders, or metabolic conditions. It may also be part of a broader evaluation for research or specialized clinical studies.
How Is the Sample Collected?
A blood sample will be drawn from a vein, usually in your arm. The blood is then processed to separate plasma or serum for testing. This process is quick and typically done in a clinical setting.
What Does the Result Mean?
Results are interpreted based on clinical context and may not have a single standard reference range. Elevated or reduced levels could indicate underlying health concerns, but further evaluation by your doctor is needed to understand the cause and implications.
Reference range
NCBI: SCC <2.0 ng/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Heparan sulfate levels can be relevant in research or specialized studies but are not commonly used in routine diagnostics. Abnormalities may suggest conditions like mucopolysaccharidoses (a group of genetic disorders) or other metabolic or bleeding disorders. Always discuss results with your healthcare provider.
Short name
Heparan sulfate proteoglycan
Frequently asked questions
What does a heparan sulfate test measure?
How is this test different from other blood tests?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy