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Hepatitis B and Hepatitis C Antibody Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to hepatitis B and hepatitis C viruses in your blood. Antibodies are your body’s way of fighting off infections, so this helps determine if you’ve been exposed to these viruses.

Quick summary

["This test helps identify past or current infections with hepatitis B or C, guiding further medical evaluation if needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42191-7
Short code
Hepatitis A+B+C 7a Pnl Ser
Synonyms
Hepatitis A+B+C 7a Pnl Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
87340
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have risk factors for hepatitis, such as unprotected sexual contact, sharing needles, or living with someone who has hepatitis. It’s also used during pregnancy to check for infection or if you’ve had an organ transplant.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a small needle inserted into your arm to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. If you’re pregnant or have a bleeding disorder, let your provider know before the test.

What the Test Results Mean

Positive results for specific antibodies (e.g., HBsAb for hepatitis B or anti-HCV for hepatitis C) suggest past infection or immunity. Negative results mean you currently do not have detectable antibodies for these viruses. Follow-up testing may be needed to confirm or rule out infection.

Common Causes of Abnormal Results

False negatives can occur if the test is taken too early after exposure. False positives are rare but may happen with certain conditions or medications. If results are unclear, additional testing may be required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting hepatitis antibodies is critical for early diagnosis, treatment planning, and preventing spread. If you test positive, your doctor will guide you on next steps, which may include further testing, vaccination (for hepatitis B), or monitoring for chronic infection.

Short name

Hepatitis Antibody Screen

Frequently asked questions

What does a positive result mean for me?
A positive result for hepatitis antibodies means your body has recognized these viruses, which could indicate past infection or immunity. Your doctor will discuss next steps, such as additional tests or vaccination (for hepatitis B), based on your specific antibodies detected.
Will I need to take any special steps if my test is positive?
If you test positive, follow your doctor’s advice carefully. This may include avoiding activities that increase infection risk (e.g., sharing needles), getting vaccinated (for hepatitis B), or undergoing further testing to assess chronic infection status.
Can I still get hepatitis even if my antibody test is negative?
Yes, a negative antibody test means you currently lack detectable antibodies, but you could still be at risk of infection if exposed. Practice safe behaviors (e.g., vaccination, protection during sex, avoiding shared needles) to lower your risk.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy