Liver Function Test Panel (Serum) – Enzymatic and Protein-Based

What This Test Measures

Your blood sample will be tested for several liver-related markers, including enzymes like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which indicate liver cell damage. It may also measure bilirubin (a waste product from red blood cells), albumin (a protein made by the liver), and possibly alkaline phosphatase (ALP) or gamma-glutamyl transferase (GGT) depending on the specific panel. These tests together give a picture of how well your liver is functioning.

Why It’s Done

Doctors order this test when you have symptoms like jaundice (yellowing of skin/eyes), fatigue, abdominal pain, or if you’ve been exposed to liver-damaging substances (like alcohol or certain medications). It’s also used to monitor chronic liver diseases or before/after treatments for liver conditions.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if certain enzymes (like ALT or AST) are being measured. Avoid alcohol for 24 hours before testing. Bring any medications or supplements you’re taking, as they can affect results.

What to Expect During the Test

A healthcare provider will draw blood from a vein in your arm. It usually takes a few minutes, and you may feel a slight pinch. The blood is then sent to a lab for analysis.