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Hepatitis A Virus Antibody, IgM (Serum) – Reverse Passive Hemagglutination Test

Published: August 9, 2026Updated: August 16, 2026

This test detects IgM antibodies to the hepatitis A virus in your blood, which can help identify recent infection.

Quick summary

["Recent hepatitis A exposure may be suspected if this antibody is present."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29482-7
Short code
Hep v A-wave reversal.max exp DOP
Synonyms
Hep v A-wave reversal.max exp DOP
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-doppler
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for IgM antibodies specific to the hepatitis A virus. IgM antibodies are typically produced shortly after infection and can indicate an acute (recent) hepatitis A virus infection. This method uses reverse passive hemagglutination to detect these antibodies in serum.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like fever, fatigue, nausea, or jaundice, or if you’ve recently traveled to areas with higher hepatitis A risk. It may also be used to confirm exposure in individuals with known risk factors.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The serum portion is separated and tested for IgM antibodies using a specialized laboratory technique.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally, but inform your provider if you’re on any medications that could affect blood tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive IgM results suggest recent hepatitis A infection and may prompt further evaluation or vaccination guidance. Negative results do not rule out infection if tested too early or if the test was not properly interpreted. This test is not used for monitoring chronic infection or vaccination status.

Short name

IgM Hepatitis A Antibody (Reverse PAH)

Frequently asked questions

When might I get this test?
Your healthcare provider may recommend this test if you have symptoms of hepatitis A, recent travel to high-risk areas, or exposure to someone with hepatitis A.
What does a positive result mean?
A positive result indicates the presence of IgM antibodies to hepatitis A, which suggests you may have been recently infected. Follow-up may include additional testing or vaccination consultation.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy