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Hepatitis B surface antibody, total (qualitative/quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the hepatitis B virus surface antigen, which may indicate past infection, immunity, or exposure to the virus.

Quick summary

["Helps assess immunity or exposure to hepatitis B virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49776-8
Short code
HEV Ab Ser IA-aCnc
Synonyms
HEV Ab Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have risk factors for hepatitis B, such as recent travel to areas with high transmission rates, exposure to infected blood, or if you’re pregnant or have a chronic condition that increases risk. It can also be used to confirm immunity after vaccination or monitor for infection in people who may have been exposed.

What to Expect Before the Test

No special preparation is needed. A small needle will be used to draw blood from a vein in your arm. You may feel a slight pinch, but the procedure usually takes only a few minutes.

What the Test Results Mean

Results can be qualitative (positive/negative) or quantitative (measuring antibody levels). Positive results suggest immunity or past infection; further testing may be needed to confirm active infection. Negative results mean no detectable antibodies, which may require additional evaluation if risk factors are present.

Common Reasons for Testing

This test is often used in screening for hepatitis B, especially in high-risk groups like healthcare workers, travelers, or individuals with multiple sexual partners. It can also be part of routine check-ups for those who have received the hepatitis B vaccine.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hepatitis B Antibody Screen/Confirm

Frequently asked questions

What does a positive result mean?
A positive result for hepatitis B surface antibodies may indicate you have immunity from vaccination or past infection. However, if you’re unsure about vaccination status, further testing (like hepatitis B core antibody) may be needed to confirm.
How does this differ from hepatitis B core antibodies?
Hepatitis B surface antibodies detect immunity or past exposure, while hepatitis B core antibodies (IgM or IgG) indicate active infection or recent exposure. This test alone cannot distinguish between these states.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy