Hepatitis B surface antibody, total (qualitative/quantitative)
This test detects antibodies to the hepatitis B virus surface antigen, which may indicate past infection, immunity, or exposure to the virus.
["Helps assess immunity or exposure to hepatitis B virus."]
Key facts at a glance
- LOINC
- 49776-8
- Short code
- HEV Ab Ser IA-aCnc
- Synonyms
- HEV Ab Ser IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have risk factors for hepatitis B, such as recent travel to areas with high transmission rates, exposure to infected blood, or if you’re pregnant or have a chronic condition that increases risk. It can also be used to confirm immunity after vaccination or monitor for infection in people who may have been exposed.
What to Expect Before the Test
No special preparation is needed. A small needle will be used to draw blood from a vein in your arm. You may feel a slight pinch, but the procedure usually takes only a few minutes.
What the Test Results Mean
Results can be qualitative (positive/negative) or quantitative (measuring antibody levels). Positive results suggest immunity or past infection; further testing may be needed to confirm active infection. Negative results mean no detectable antibodies, which may require additional evaluation if risk factors are present.
Common Reasons for Testing
This test is often used in screening for hepatitis B, especially in high-risk groups like healthcare workers, travelers, or individuals with multiple sexual partners. It can also be part of routine check-ups for those who have received the hepatitis B vaccine.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Hepatitis B Antibody Screen/Confirm
Frequently asked questions
What does a positive result mean?
How does this differ from hepatitis B core antibodies?
Can I get this test at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy