Hepatitis E Virus IgG Antibody, Serum (Quantitative Immunoassay)
This test measures the presence of antibodies against the Hepatitis E virus in your blood. These antibodies develop after your body has been exposed to the virus.
["Your body’s immune response to Hepatitis E can be detected with this simple blood test."]
Key facts at a glance
- LOINC
- 104414-8
- Short code
- HEV IgG sp2 Titr Ser IA
- Synonyms
- HEV IgG sp2 Titr Ser IA
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test to check for past exposure to Hepatitis E virus. It’s particularly useful if you’ve traveled to areas with higher risk, have symptoms of liver infection, or have conditions that weaken your immune system. This test helps determine if you’ve had an infection that your body has successfully fought off, rather than actively being infected now.
What Does the Test Measure?
The test detects IgG antibodies, which are produced by your immune system after an infection has occurred. Unlike IgM antibodies (which appear during an active infection), IgG antibodies remain in your blood for a longer period, indicating past exposure to the virus.
What Does a Positive Result Mean?
A positive result means your body has likely been exposed to Hepatitis E virus at some point. This does not necessarily mean you currently have an active infection, but it confirms you’ve had an immune response to the virus. Further testing may be needed to determine if symptoms are related to this past exposure.
What Does a Negative Result Mean?
A negative result suggests you either have never been exposed to Hepatitis E virus or your body hasn’t produced detectable antibodies yet. However, this doesn’t rule out a recent infection—your body may still be producing IgM antibodies, which are not measured in this test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is important for identifying past infections with Hepatitis E, which can be transmitted through contaminated water or food. While Hepatitis E is usually mild in healthy individuals, it can be severe in pregnant women or those with weakened immune systems. Detecting past exposure helps in planning preventive measures, especially if you’re at higher risk for future infection.
Short name
IgG Antibody to Hepatitis E Virus
Frequently asked questions
What are the possible reasons for ordering this test?
How is the test performed?
Can I have false results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy