Skip to content

Serum or Plasma Protein Electrophoresis with Bromocresol Green (BCG) Dye Binding Assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood using electrophoresis and a dye called bromocresol green. It helps identify patterns of protein concentration that may indicate conditions like infections, inflammation, or certain blood disorders.

Quick summary

["This test helps doctors check protein balance in your blood and spot potential health issues early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90460-7
Short code
HEV RNA SerPl Ql NAA+probe
Synonyms
HEV RNA SerPl Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What the Test Measures

Electrophoresis separates blood proteins based on size and charge, creating bands that reflect different protein groups (e.g., albumin, globulins). The BCG dye binds to albumin, allowing for precise measurement of its concentration relative to other proteins. This helps assess overall protein distribution and identify abnormalities.

Why It’s Done

Doctors may order this test to diagnose or monitor conditions such as multiple myeloma, chronic liver disease, nephrotic syndrome, or other protein-related disorders. It’s also used in screening for conditions like infections or autoimmune diseases that affect protein levels.

Sample Collection

A blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate serum or plasma for testing. This test can be performed on fresh or stored samples, depending on clinical needs.

Preparation

No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could interfere with results (e.g., certain supplements or high-protein diets). Follow your healthcare provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in identifying imbalances in blood proteins, which can signal underlying health problems. For example, abnormal patterns may reveal conditions like liver disease (reduced albumin), multiple myeloma (elevated monoclonal proteins), or inflammatory diseases (altered globulin levels). Early detection can guide treatment decisions.

Short name

BCG Protein Electrophoresis

Frequently asked questions

What does a high or low protein result mean?
High or low protein levels alone don’t indicate a specific condition. Instead, the pattern of protein bands and their relative concentrations help doctors diagnose issues like infections, cancers, or organ dysfunction. Your results will be interpreted alongside your medical history and other tests.
How long will I need to wait for results?
Results are typically available within 24 to 72 hours, depending on lab processing times. Your healthcare provider will contact you once they’re ready to discuss them with you.
Can I fast before this test?
No fasting is required for this test, as it measures proteins in your blood rather than substances like glucose or lipids. However, always confirm with your healthcare provider if you have any specific instructions for your test.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy