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Serum Albumin Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the protein composition of your blood serum using electrophoresis to separate and analyze albumin and other proteins.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like liver disease or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4557-5
Short code
Hgb Abruz Bld Ql Elph Alk
Synonyms
Hgb Abruz Bld Ql Elph Alk
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
3.5
Ref high
5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis-ph
CPT
84132
SNOMED
110742001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Albumin Electrophoresis Used For?

Albumin electrophoresis is primarily used to detect abnormalities in protein distribution, such as hypoalbuminemia (low albumin levels) or the presence of abnormal proteins like paraproteins. This can help diagnose conditions like multiple myeloma, liver disease, or nephrotic syndrome.

How Is the Sample Collected?

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum, which is sent to the lab for electrophoresis analysis.

What Might Abnormal Results Indicate?

Abnormal results may show altered protein bands, indicating conditions like liver dysfunction, kidney disease, or the presence of monoclonal proteins (e.g., in multiple myeloma). Some patients may also have elevated or reduced levels of globulins or other proteins.

Preparation for the Test

No special preparation is needed for this test. However, inform your healthcare provider about any medications you’re taking, as certain drugs (e.g., steroids) may affect protein levels.

Reference range

Adult: 3.5-5.0 mmol/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Albumin electrophoresis plays a key role in diagnosing and monitoring conditions affecting protein synthesis, storage, or breakdown. For example, it helps identify monoclonal gammopathies (e.g., multiple myeloma) by detecting abnormal protein spikes, while liver or kidney disease may cause shifts in albumin and globulin levels.

Short name

Albumin Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend albumin electrophoresis if they suspect conditions like liver disease, kidney disease, or a rare blood disorder (e.g., multiple myeloma). It can also help evaluate protein abnormalities in chronic illnesses or after certain treatments.
What does it mean if my results show unusual protein bands?
Unusual bands may indicate an underlying condition affecting protein production or breakdown. For example, a prominent spike could signal multiple myeloma, while a reduced albumin level might point to liver or kidney issues. Always discuss results with your healthcare provider.
Do I need to fast before this test?
No fasting is required for albumin electrophoresis. However, if you’re also having other blood tests, follow any fasting instructions provided by your lab or doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy