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Serum or Plasma Hemoglobin A1c Electrophoresis (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the percentage of hemoglobin variants, including Hemoglobin A1c, in your blood using electrophoresis. It helps assess long-term blood sugar control.

Quick summary

["This test helps doctors check how well your blood sugar has been managed over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20572-4
Short code
Hgb A MFr Bld Elph
Synonyms
Hgb A MFr Bld Elph
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates hemoglobin types based on their electrical charge. Hemoglobin A1c (a form linked to chronic glucose levels) is often analyzed alongside other variants. This method may be used qualitatively (to detect presence) or quantitatively (to measure specific percentages).

Why It’s Done

Doctors may order this test if you have diabetes or prediabetes, or if you’re at risk for complications related to blood sugar control. It can also help monitor treatment effectiveness or screen for conditions like thalassemia or other hemoglobin disorders.

How It Works

A small blood sample is drawn, and the hemoglobin is separated into different types using an electric field. The results show the distribution of hemoglobin variants, including A1c, which reflects average blood sugar over the past 2–3 months.

What the Results Mean

Results may show elevated or reduced levels of specific hemoglobin types, which can indicate conditions like diabetes, hereditary blood disorders, or other metabolic issues. Exact interpretation depends on clinical context and your doctor’s guidance.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c Electrophoresis

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss findings.
Can this test replace a standard HbA1c measurement?
No, this test provides additional hemoglobin variant details but is not a substitute for standard HbA1c tests, which are the primary measure for diabetes management. Your doctor may use both for comprehensive assessment.
What if my results show unusual hemoglobin variants?
Unusual variants may signal hereditary blood disorders (e.g., thalassemia) or other conditions. Your doctor will review results with you and may recommend further testing or genetic evaluation if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy