Hemoglobin Mass Fraction by Flow Cytometry (Red Blood Cell Analysis)
This test measures the proportion of hemoglobin within your red blood cells using flow cytometry. It helps assess red blood cell health and potential abnormalities in hemoglobin distribution.
["This test helps evaluate red blood cell function and identify conditions affecting hemoglobin levels."]
Key facts at a glance
- LOINC
- 71876-7
- Short code
- Hgb A MFr.DF Bld
- Synonyms
- Hgb A MFr.DF Bld
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Measuring?
Flow cytometry is a technique that analyzes the size, shape, and internal components of cells, including hemoglobin content. By measuring the mass fraction of hemoglobin in your red blood cells, this test can provide insights into their overall health and functionality. It may be used alongside other blood tests to diagnose conditions like anemia or hemolytic disorders.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like fatigue, pale skin, or unusual bruising, or if they suspect conditions such as thalassemia, sickle cell disease, or other hemoglobin-related disorders. It can also be part of a broader evaluation for unexplained anemia or blood abnormalities.
How Is the Sample Collected?
A small amount of blood is drawn from a vein in your arm, typically in a clinic or lab setting. The blood sample is then processed to isolate red blood cells for analysis.
What Do the Results Mean?
Results provide a qualitative or quantitative assessment of hemoglobin distribution within red blood cells. Abnormal findings may indicate issues such as increased or decreased hemoglobin content, which can guide further diagnostic steps or treatment planning.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Hemoglobin Mass Fraction (RBC)
Frequently asked questions
How often do I need this test?
What are the typical reference ranges for this test?
Can I prepare for this test in any special way?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy