Hemoglobin Electrophoresis (for Alpha-1 Antitrypsin and Other Globulin Fractions)
This test measures the separation of proteins in your blood using electrophoresis, helping identify levels of alpha-1 antitrypsin and other globulin proteins.
["Electrophoresis helps diagnose conditions affecting protein balance in your blood."]
Key facts at a glance
- LOINC
- 4559-1
- Short code
- Hgb Barts Bld Ql Elph Alk
- Synonyms
- Hgb Barts Bld Ql Elph Alk
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 84132
- SNOMED
- 110742001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins based on their electrical charge, allowing for the detection of specific protein fractions, including alpha-1 antitrypsin and globulins. This method helps distinguish abnormal protein patterns that may indicate genetic disorders or other health conditions.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like chronic lung disease, liver problems, or if you have a family history of alpha-1 antitrypsin deficiency. It can also be used to screen for other protein-related disorders.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for electrophoresis analysis.
Common Conditions Evaluated
This test is particularly useful in diagnosing alpha-1 antitrypsin deficiency, a genetic condition that can lead to lung or liver disease. It may also help identify other globulin-related abnormalities.
Reference range
Adult: 3.5-5.0 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Alpha-1 Antitrypsin and Globulin Profile
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Is there anything I should do before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy