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Hemoglobin A1c (HbA1c) with 24-hour urine collection for quantitative measurement of total urinary hemoglobin

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of hemoglobin (the protein in red blood cells that carries oxygen) found in your urine over a 24-hour period. It helps assess how much hemoglobin is excreted, which can be relevant in certain blood disorders or conditions.

Quick summary

["This test helps monitor hemoglobin loss in urine, which may indicate underlying blood-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4560-9
Short code
Hgb Bethes Bld Ql
Synonyms
Hgb Bethes Bld Ql
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms or risk factors for conditions like hemolytic anemia (where red blood cells break down too quickly) or other blood disorders. It may also be used in research or specialized clinical scenarios to track urinary hemoglobin levels.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period. Typically, you’ll start by emptying your bladder at the beginning of the collection period and then collect every urine void until you finish at the end of the day. Store the urine in a cool container if needed.

How the Test Works

The collected urine is analyzed to measure the total amount of hemoglobin present. This is done using a specialized laboratory method to quantify hemoglobin concentration in your urine sample.

What the Results Mean

Results are typically reported as a mass concentration of hemoglobin in urine. While specific reference ranges can vary by lab, higher than expected levels may suggest conditions like hemolysis (destruction of red blood cells) or certain genetic disorders.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HbA1c Urine Hb Quantification

Frequently asked questions

What does my test result indicate?
Your result will be compared to lab-specific reference ranges. Elevated levels may indicate abnormal red blood cell breakdown or conditions affecting urine hemoglobin excretion. Your healthcare provider will discuss these findings in the context of your overall health and symptoms.
How often should I get this test?
This test is not a routine screening test for most people. It may be ordered as needed based on your medical history, symptoms, or specific clinical circumstances. Your provider will determine the frequency based on your situation.
Can I take medications before this test?
Generally, you should avoid certain medications that might affect urine color or hemoglobin levels, such as certain pain relievers or supplements. Always follow your provider’s specific instructions for test preparation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy