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Hemoglobin mass concentration in whole blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of hemoglobin (the oxygen-carrying protein in red blood cells) in your blood, not just the percentage or amount of hemoglobin present.

Quick summary

["Helps assess red blood cell health and overall blood oxygen-carrying capacity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40719-7
Short code
Hgb BldCo-mCnc
Synonyms
Hgb BldCo-mCnc
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Hemoglobin Mass Used For?

Hemoglobin mass testing is primarily used to diagnose and monitor conditions affecting red blood cells, such as anemia (low red blood cell count) or polycythemia (high red blood cell count). It can also help evaluate iron deficiency or other blood disorders where red blood cell production or function is impaired.

How Is This Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The sample is then analyzed using a specialized technique to measure the precise amount of hemoglobin in your blood.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like fatigue, pale skin, shortness of breath, or if they suspect conditions like anemia, thalassemia, or other blood-related disorders.

What Do the Results Mean?

Results are compared to standard ranges for your age, sex, and overall health. Abnormal results may indicate whether you have too little or too much hemoglobin, guiding further medical evaluation.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Hemoglobin mass is a critical indicator of red blood cell health and overall blood health. Low levels can signal anemia or iron deficiency, while high levels may suggest conditions like polycythemia or dehydration. It provides a more precise measurement than traditional hemoglobin percentage tests, helping doctors diagnose and manage blood disorders more accurately.

Short name

Hemoglobin Mass

Frequently asked questions

Why is hemoglobin mass testing different from regular hemoglobin tests?
Hemoglobin mass testing measures the absolute amount of hemoglobin in your blood, whereas traditional hemoglobin tests often measure the concentration (percentage) of hemoglobin in relation to red blood cell volume. This distinction helps in diagnosing specific blood disorders more accurately.
How often should I get this test?
The frequency depends on your health condition and medical needs. Your healthcare provider will determine how often you need this test based on your symptoms, diagnosis, and treatment plan.
Can I prepare for this test?
No special preparation is usually needed. However, inform your healthcare provider about any medications or conditions that might affect blood results, such as recent blood donations or certain medications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy