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Hemoglobin A1c (HbA1c) measured by high-performance liquid chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past 2 to 3 months by examining your red blood cells.

Quick summary

["HbA1c reflects your long-term blood sugar control and helps doctors monitor diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97555-7
Short code
Hgb BldCV Oximetry-mCnc
Synonyms
Hgb BldCV Oximetry-mCnc
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
oximetry
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why is HbA1c important?

HbA1c provides a snapshot of how well your blood sugar has been controlled over time, regardless of daily fluctuations. It’s a key tool for diagnosing diabetes and assessing treatment effectiveness, especially in people with type 1 or type 2 diabetes.

How is HbA1c different from checking blood sugar levels?

Unlike quick blood sugar tests (e.g., fingerstick glucose checks), HbA1c doesn’t depend on recent eating habits or activity levels. It’s based on the percentage of hemoglobin molecules coated with sugar, which builds up gradually over months.

What does a high or low HbA1c mean?

A high HbA1c (typically above 7%) suggests poor blood sugar control and may indicate diabetes or prediabetes. A low HbA1c (below 5.7%) could mean your blood sugar is consistently well-controlled, but this isn’t always reliable without clinical context.

What affects HbA1c results?

Factors like pregnancy, certain medications (e.g., birth control pills), blood disorders, or recent blood transfusions can temporarily alter HbA1c levels. Always discuss these with your doctor.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: HbA1c is critical for diabetes management because it helps prevent long-term complications like nerve damage, kidney disease, or heart problems by identifying trends in blood sugar control.

Short name

HbA1c

Frequently asked questions

Why do I need an HbA1c test?
Your doctor may order this test to diagnose diabetes, check if your current treatment plan is working, or monitor prediabetes progression. It’s also useful for people with diabetes who want to track their progress over time.
What should I do if my HbA1c is high?
Work with your healthcare team to adjust diet, exercise, or medication as needed. Lifestyle changes like eating balanced meals, staying active, and managing stress can help lower HbA1c levels.
Does diet or exercise affect HbA1c results?
Yes! While HbA1c reflects long-term trends, short-term diet or exercise changes won’t immediately alter it. Focus on consistent habits to see gradual improvements over weeks or months.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy