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Hemoglobin A1c (HbA1c) by Electrophoresis on Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the percentage of hemoglobin that is coated with sugar, reflecting your average blood sugar levels over the past 2–3 months.

Quick summary

["Helps track long-term diabetes management and glucose control."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4565-8
Short code
Hgb Chesap Bld Ql Elph Acid
Synonyms
Hgb Chesap Bld Ql Elph Acid
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis-ph
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is HbA1c Used For?

HbA1c is primarily used to diagnose diabetes, assess how well your blood sugar is managed over time, and guide treatment decisions. It’s a key tool for people with diabetes to monitor their condition and adjust their care plan accordingly.

How Is This Test Performed?

A small blood sample is taken from your arm, typically during a routine visit to your healthcare provider. The blood is then analyzed using electrophoresis, a method that separates hemoglobin types based on their electrical charge.

Why Is HbA1c Important?

Unlike daily blood sugar checks, HbA1c gives a broader picture of your blood sugar trends, helping prevent complications like nerve damage, kidney disease, or vision problems. It’s a reliable indicator of how well your body handles glucose over time.

What Does a High or Low HbA1c Mean?

A higher HbA1c level (typically above 6.5%) suggests poor blood sugar control and may indicate diabetes or prediabetes. A lower level (below 5.7%) may indicate excellent control, but this depends on your overall health and medical history.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: HbA1c is a gold-standard marker for chronic hyperglycemia, used to diagnose diabetes (when ≥6.5%), screen for prediabetes (5.7–6.4%), and evaluate glycemic control in patients with diabetes. It reduces reliance on short-term glucose measurements and provides a more stable reflection of metabolic health.

Short name

HbA1c (Blood Sugar Control)

Frequently asked questions

How often should I get an HbA1c test?
Your healthcare provider will determine how often you need this test based on your diabetes management plan. Typically, people with diabetes may get it every 3–6 months to monitor progress and adjust treatments.
Can HbA1c be affected by factors like iron deficiency or anemia?
Yes, certain conditions like iron deficiency or hemoglobin disorders can influence HbA1c results. If you have these conditions, your provider may use additional tests or adjust interpretations of your HbA1c level.
Does diet or exercise affect HbA1c results?
While diet and exercise directly impact your daily blood sugar levels, HbA1c reflects long-term trends. Small fluctuations in your diet or activity over weeks can influence your HbA1c, so consistent management is key.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy