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Serum Protein Electrophoresis with Bromocresol Green Staining

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood serum using electrophoresis and a dye called bromocresol green. It helps identify abnormalities in protein patterns that may suggest conditions like multiple myeloma, liver disease, or other disorders affecting protein synthesis or breakdown.

Quick summary

["Electrophoresis helps doctors spot unusual protein patterns that could signal hidden health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4567-4
Short code
Hgb CSp Bld Ql Elph Acid
Synonyms
Hgb CSp Bld Ql Elph Acid
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis-ph
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect conditions like multiple myeloma (a cancer of plasma cells), chronic liver disease, or other disorders that alter protein levels in the blood. It’s also used to monitor treatment progress or screen for conditions affecting protein metabolism.

How the Test Works

A small blood sample is drawn and separated into different protein fractions based on size and charge. The bromocresol green dye binds to specific proteins, creating visible bands that indicate their relative amounts. These bands are then analyzed to detect any unusual patterns.

What to Expect Before the Test

No special preparation is needed, but you may want to avoid eating or drinking for a few hours before the blood draw if instructed. Wear a loose shirt for easy access to your arm.

What to Expect During the Test

A healthcare professional will insert a needle into your arm to draw blood. You may feel a slight pinch, but the process usually takes just a few minutes. You can sit or lie down comfortably during the procedure.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Protein Electrophoresis (BCG)

Frequently asked questions

What Does an Abnormal Result Mean?
Abnormal protein patterns may indicate conditions like multiple myeloma (where abnormal proteins, such as monoclonal gammopathy, appear), liver disease (where albumin levels drop), or other metabolic disorders. Your provider will discuss findings with you based on your medical history and symptoms.
How Often Should I Get This Test?
The frequency depends on your health needs. Some patients get it every few months to monitor chronic conditions, while others may need it only occasionally for screening or follow-up.
Can I Fast Before This Test?
Generally, no fasting is required unless your provider specifies it. However, always follow their instructions to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy