Hemoglobin Subtype Analysis by Electrophoresis (Auto) - Serum
This test measures the different types of hemoglobin in your blood using electrophoresis, a method that separates hemoglobin variants based on their electrical charge. It helps identify conditions affecting hemoglobin structure, such as sickle cell disease or other inherited blood disorders.
["This test helps diagnose or monitor conditions related to abnormal hemoglobin."]
Key facts at a glance
- LOINC
- 73895-5
- Short code
- Hgb EntSub Retic Auto
- Synonyms
- Hgb EntSub Retic Auto
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms like fatigue, pain, or unusual blood test results that suggest a hemoglobin disorder. It’s also used in screening or diagnosing conditions like sickle cell disease, thalassemia, or other inherited blood disorders.
How the Test Works
A small blood sample is taken from your arm. The serum (liquid part of blood after clotting) is then analyzed using electrophoresis, which separates hemoglobin into different bands based on their electrical properties. Each band represents a specific type of hemoglobin.
What to Expect Before the Test
No special preparation is needed for this test. You may have a slight bruise or discomfort at the injection site, but this usually fades quickly. If you’re on blood-thinning medication, let your provider know before the test.
What to Expect During the Test
The test involves a quick venipuncture (blood draw) from your arm. The process is quick and typically painless. You may feel a slight pinch, but most people tolerate it well. The serum is then processed in a lab for analysis.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal hemoglobin patterns detected by this test can indicate inherited blood disorders like sickle cell disease, thalassemia, or other hemoglobinopathies. These conditions can cause anemia, chronic pain, or other complications. Early detection allows for better management and treatment planning.
Short name
Hemoglobin Electrophoresis
Frequently asked questions
What does an abnormal result mean?
How often should I get this test?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy