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Hemoglobin Fraction: Fractured Blood Cell Index (Serum/Plasma Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific components of hemoglobin in your blood, often used to assess red blood cell health or detect conditions affecting hemoglobin structure.

Quick summary

["Helps identify potential blood disorders by examining hemoglobin fragments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78748-1
Short code
Hgb Fract Bld CE-Imp
Synonyms
Hgb Fract Bld CE-Imp
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
capillary-electrophoresis
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates hemoglobin breakdown products, which may reflect abnormalities in red blood cells such as fragmentation or structural defects. This can be part of broader evaluations for conditions like microangiopathic hemolytic anemia or hereditary hemolytic anemias.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fatigue, pale skin, or unexplained anemia, or if you’re being evaluated for conditions that cause red blood cell damage or fragmentation.

Common Conditions Monitored

This test can help diagnose or monitor conditions where red blood cells are unusually fragmented, such as thrombotic thrombocytopenic purpura (TTP) or certain types of hemolytic anemia.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is processed to separate serum or plasma for testing. This test is usually performed on fresh or stored samples, depending on the lab’s protocol.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Hemoglobin Fraction Analysis

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on the lab’s workflow and whether additional testing or confirmatory steps are needed.
Can I eat or drink before this test?
No special preparation is required for this test. However, follow any general fasting instructions your healthcare provider may have given for other blood tests.
What are the normal values for this test?
Reference ranges vary by lab and may not be standardized. Your results will be compared to your own baseline or clinical context rather than a single set of general values.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy