Hemoglobin F Percentage in Whole Blood by Electrophoresis
This test measures the proportion of fetal hemoglobin (HbF) in your blood, which is naturally present in newborns but typically decreases over time. It may be used to assess conditions affecting red blood cell production or hemoglobin structure.
["HbF percentage helps diagnose or monitor certain blood disorders and genetic conditions."]
Key facts at a glance
- LOINC
- 50791-3
- Short code
- Hgb Fract Bld Elph pH6.0-Imp
- Synonyms
- Hgb Fract Bld Elph pH6.0-Imp
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms like anemia, fatigue, or unusual blood test results. It could also be part of screening for conditions such as thalassemia, sickle cell disease, or other hemoglobinopathies. Sometimes, it’s checked in newborns or during pregnancy for early detection of genetic risks.
What Does the Result Mean?
Results can vary based on age, health status, and underlying conditions. Higher-than-expected levels might indicate conditions like beta-thalassemia or certain cancers, while lower levels could suggest inherited blood disorders. Your doctor will interpret the result in the context of your medical history and other tests.
How Is the Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The sample is then analyzed using electrophoresis, a technique that separates different types of hemoglobin based on their electrical charge. This process helps identify the proportion of fetal hemoglobin among other hemoglobin types.
What Are Possible Results?
There are no standard reference ranges provided here because they depend on factors like age, medical history, and specific clinical context. Your doctor will discuss what your result means for you.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HbF % (Electrophoresis)
Frequently asked questions
What causes abnormal HbF levels?
How often should I get this test?
Can lifestyle changes affect HbF levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy