Free Ceruloplasmin Concentration (Serum)
This test measures the amount of ceruloplasmin protein in your blood that is not bound to copper. Ceruloplasmin is a protein that helps transport copper in the blood and has antioxidant properties.
["Understanding your free ceruloplasmin levels may help assess copper metabolism and potential copper storage disorders."]
Key facts at a glance
- LOINC
- 49000-3
- Short code
- Hgb Free CSF Ql
- Synonyms
- Hgb Free CSF Ql
- Category
- hematology
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Is Ceruloplasmin?
Ceruloplasmin is a copper-binding protein produced mainly by the liver. It plays a key role in transporting copper throughout the body and also acts as an antioxidant by neutralizing free radicals. While total ceruloplasmin levels are often measured, free ceruloplasmin specifically indicates the portion of ceruloplasmin that is unbound to copper.
Why Might This Test Be Ordered?
Your healthcare provider may order this test if you have symptoms or risk factors for conditions like Wilson’s disease (a copper storage disorder) or other copper-related metabolic issues. It may also be used in research or specialized diagnostic contexts to evaluate copper metabolism.
How Is the Test Performed?
A blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate the serum (liquid part of blood without clotting factors) and analyzed for free ceruloplasmin levels using a specialized laboratory technique.
What Does the Result Mean?
Results are interpreted by your healthcare provider based on your clinical picture, symptoms, and other lab tests. Abnormal levels may suggest copper metabolism disorders or other health concerns, but they are not standalone diagnoses.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Free Ceruloplasmin in Health and Disease
Short name
Free Ceruloplasmin
Frequently asked questions
How often will I need this test?
What are the normal ranges for this test?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy