Hemoglobin F (Fraction) by Electrophoresis
This test measures the percentage of fetal hemoglobin (HbF) in your blood, which is naturally present in newborns and some adults with certain blood disorders.
["HbF levels help diagnose or monitor conditions like thalassemia or sickle cell disease."]
Key facts at a glance
- LOINC
- 89364-4
- Short code
- Hgb Free Fld-mCnc
- Synonyms
- Hgb Free Fld-mCnc
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms of anemia, unexplained fatigue, or if you’re pregnant and at risk for conditions affecting fetal hemoglobin. It can also be part of routine screening for blood disorders in certain populations.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood, similar to a routine blood test. The process usually takes a few minutes.
How the Results Are Used
Results help determine if you have an inherited blood disorder or if fetal hemoglobin levels are abnormal. High levels may indicate conditions like beta-thalassemia or polycythemia vera, while low levels might suggest other blood-related issues.
What the Results Mean
While reference ranges vary by lab, abnormal results may prompt further testing or additional questions about your medical history and symptoms. Your provider will discuss findings with you in detail.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated HbF levels can be associated with certain genetic blood disorders, such as thalassemia or sickle cell trait, which may require ongoing monitoring or treatment. Low levels may also indicate conditions affecting red blood cell production or function. Always consult your healthcare provider for interpretation of your specific results.
Short name
HbF Fraction
Frequently asked questions
What causes abnormal HbF levels?
How long does it take to get results?
Can lifestyle changes affect HbF levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy