Free Hemoglobin in Plasma (Mass Concentration)
This test measures the amount of free hemoglobin (the protein that carries oxygen in your blood) that is not bound to other substances in your plasma.
["Helps assess conditions affecting red blood cells or blood breakdown."]
Key facts at a glance
- LOINC
- 721-1
- Short code
- Hgb Free Plas-mCnc
- Synonyms
- Hgb Free Plas-mCnc
- Category
- hematology
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may request this test if you have symptoms like fatigue, pale skin, or unusual bruising, or if they suspect conditions such as hemolysis (red blood cell destruction), anemia, or certain blood disorders. It can also help monitor treatments for blood-related conditions.
What to Expect Before the Test
You’ll typically have a small needle inserted into your arm to draw a blood sample. This is usually quick and painless. No special preparation is needed, but inform your doctor about any medications or supplements you take.
How the Test Results Are Used
Results help doctors diagnose or monitor conditions affecting red blood cells, such as whether your body is breaking down red blood cells too quickly or if there’s an issue with how hemoglobin functions in your blood.
Common Conditions Monitored
This test is often used alongside other blood tests to check for hemolytic anemia, sickle cell disease, or conditions involving abnormal hemoglobin production.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Free Hemoglobin Plasma
Frequently asked questions
What does a high free hemoglobin level mean?
What does a low free hemoglobin level mean?
Does this test require fasting?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy